Medical Device Coating Particulate

Posted by Josh Simon on Tue, May 24, 2011 @ 07:27

At the time of this writing, there is no official FDA Guidance Document detailing allowable particulate from medical devices.  You can imagine that this would be an issue especially in blood-contacting applications.  Particulate escaping into the vasculature can ultimately accumulate in the brain, occluding small vessels and leading to ischemic stroke.  At the very least, insoluble particulates will accumulate in the lymph nodes where they may just hang out forever, participating in a life-long chronic immune response in much the same way those ink particles in your tatoo are doing.

Word reaching my ears from the street is that the FDA is concerned about particulate in medical devices and is asking companies who are developing catheters and other blood contacting devices to run particulate tests.  Since there is no official medical device particulate test, it looks like they are requesting USP 788.

USP 788 is actually a test for particulates in injectible formulations.  It involves streaming a liquid exudate from a device through a sensor that can count the particles, usually with a laser.  Some of the newer equipment used for this can even "see" clear particles and count them.  For medical devices, it looks like the FDA is specifically asking for "Text 1B" in the USP 788 document, which is a test for particulates in a container with a nominal volume of 100 mL.  The allowable limits are also given in the document.

ParticleCounterFor those that sell or use hydrophilic coatings, this is something to look out for.  I dare say you should even design this requirement in ahead of time, even though it is not official yet.  I believe that in the future there will be a medical device coating requirement on particulates.

Tags: medical device coating, coating particulate, USP 788, particulate testing, FDA

Hydrophilic Coatings Blog - Redesign

Posted by Josh Simon on Mon, May 23, 2011 @ 10:34

With a few minor glitches along the way, I have given the hydrophilic coatings blog a redesign and a new webhost.  Welcome to the new Hydrophilic Coatings Blog!


Old Blog Site New Blog Site
Old Hydrophilic Coatings Blog New Hydrophilic Coatings Blog

I thought I would take this time to reiterate what this site is about.  This site is aimed at customers seeking information on hydrophilic coatings, primarily for medical devices.  It is aimed at engineers and scientists in the medical field who are designing devices that might need such coatings.

The overall theme of this blog is that hydrophilic coatings are not an afterthought.  They are a sophisticated and highly technical component, and they require a lot of thought.  They are not a commodity.

On this site, I am not out to promote my own hydrophilic coating company.  I am interested in keeping an unbiased general view, so this blog can serve as a repository of information for all people in the field.  I even welcome competitors who are interested in contributing information.  Contact me if interested.

Also, please let me know if there are any obvious bugs that you can find on this site.  I am not infallible!  More seriously, I do appreciate any feedback and posts in the comments too.

Tags: Hydrophilic Coating, hydrophilic coatings, hydrophilic coatings blog

3 Tips For Using HubSpot's Blogging Application

Posted by Blog Tipster on Fri, May 20, 2011 @ 02:25

Tip 1: Embedding Video into Your Blog


To embed a video like the one above, you'll need to do the following:

  1. Most video sites like YouTube have an "embed" source code that you can copy and paste. For YouTube, this code is listed just to the right of the video itself, under a person's username.
  2. Open up the HTML Editor in HubSpot by clicking the "HTML" button in the toolbar. Then, paste in the source code at that point of the article you'd like the video to show up.
  3. Save! This tip will work on the rest of the CMS as well, not just in the blog. Just click on "Add Module", and add an HTML module. You'll be able to paste in the source code directly, and the video will exist as a stand alone module on your site.

Tip 2: Automate Your Social Media Publishing

If you use the HubSpot blogging platform, then we'll be able to automatically publish your content for you.  To set up Social Media Publishing, complete the following steps:

  1. We need to add your social media credentials before we can automate your blog publishing to their feeds. Under the Promote tab, open up HubSpot's Social Media application.
  2. Click the "Social Media Accounts" button. When prompted, add your credentials for the social media sites you'd like to publish to.
  3. Once your credentials are entered, head back to your blog's homepage and click on the "Options" link (to the right of the "Create Article" link).Your blog options will appear.
  4. Click on the Social Media Publishing tab. Under Social Media accounts, check off the boxes of the social media feeds you'd like your blog to publish to automatically. Remember to click "Update" at the bottom of the screen.
  5. When publishing content to your networks, you’ll need a line of explanatory text to let people know what they’re seeing. To write this line, write your slug in the "publishing slug" field, directly above the list of your social media acccounts. This is the text that will appear in Facebook and Twitter along with a link to the blog article.  For example, you might write "Check out my new blog post!"

Tip 3: Text Formatting 101

You can edit the fonts of your website by going to Settings > Template Configuration in HubSpot, and then click on "Advanced Configuration". Throughout this list, you'll see places where you can change the font of your different headers.

One caveat to this, however: The fonts you can use on a website are dependent on the fonts that are available on a visitor's machine. If you try to name a font that the user does not have on their computer, it will default back to something standard (usually Arial or Helvetica).

Most machines are preinstalled with dozens of fonts, so the trick is knowing which fonts are likely to be installed on which computers. For a list of the fonts supported on most browsers, view this article on Success.

Tags: HubSpot Tips